N-Acetyl-Tyrosine
N-Acetyl-Tyrosine (NALT) is a form of L-Tyrosine, an amino acid that is naturally produced in the body from another amino acid called phenylalanine. NALT supposedly has better absorption and stronger nootropic effects than L-tyrosine.
Tyrosine is commonly taken in doses of 500–2,000 mg 30–60 minutes before exercise, even though its benefits on exercise performance remain inconclusive. NALT is believed to have similar benefits to L-tyrosine, but studies haven’t confirmed this yet. However, there is good evidence that supplementing with tyrosine replenishes neurotransmitters that tend to decrease under periods of stressful or mentally demanding situations.
According to a study, tyrosine supplementation improved cognitive flexibility and working memory during a multitasking test in healthy adults. Another study found that tyrosine supplementation improved cognitive performance and reduced blood pressure during a stressful mental task in military cadets.
The recommended dosage of NALT is not established yet, but L-tyrosine is most often used in doses of 100-300 mg/kg by mouth daily. The safety profile of NALT is relatively unknown, given the lack of clinical data. Common side effects include nausea, headache, fatigue, heartburn, and joint pain.
Sources:
- https://www.verywellfit.com/the-benefits-of-tyrosine-89523
- https://supplements.selfdecode.com/blog/n-acetyl-l-tyrosine/
- https://neuropedia.com/benefits-uses-n-acetyl-l-tyrosine-nalt/
- https://nootropicsexpert.com/n-acetyl-l-tyrosine/
- https://neurohacker.com/formulation/n-acetyl-tyrosine
- https://pubchem.ncbi.nlm.nih.gov/compound/N-Acetyl-L-tyrosine