Acacetin
Acacetin is a flavone with diverse therapeutic potential in various diseases such as inflammation, cancer, obesity, viral-mediated infections, and hepatic protection. It has been reported to have anti-inflammatory and anti-cancer activity. Acacetin has also been shown to exert an antiproliferative effect by blocking cell cycle progression and inducing apoptosis. Additionally, it selectively inhibits human atrial repolarization potassium currents and prevents atrial fibrillation in dogs. The effects of acacetin on the behavior and eye morphology of Drosophila models of Alzheimer’s disease have also been studied.
The recommended dosage of acacetin has not been established yet. However, it is important to consult a healthcare professional before taking any supplements or medications. There is limited information available for toxicity profiling of acacetin.
There are no known side effects of acacetin. However, further scientific evidence is essential to validate its potency in disease models associated with inflammation and cancer.
References:
- https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/acacetin
- https://pubmed.ncbi.nlm.nih.gov/32866514/
- https://www.sciencedirect.com/science/article/pii/S0278691520305986
- https://www.nature.com/articles/srep16127
- https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.108.769554
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632086/
