Hesperidin 50%
Hesperidin 50% is a flavonoid glycoside mainly found in citrus fruits such as oranges and tangerines. It is a compound in orange peels that gives the flavonoid hesperitin to the body, and this flavonoid mediates most benefits of hesperidin including a possible increase in circulation and possible brain protective effects.
Here are some benefits of Hesperidin 50%:
- Chronic Venous Insufficiency: Hesperidin has been found to be likely effective for chronic venous insufficiency.
- Hemorrhoids: Hesperidin has been found to be effective for hemorrhoids.
- Reducing Inflammation: Animal and test tube studies suggest that hesperidin has anti-inflammatory properties.
- Reducing Oxidative Stress: Animal and test tube studies suggest that hesperidin has antioxidant properties.
- Anticancer Properties: Animal and test tube studies suggest that hesperidin has anticancer properties.
- Antimicrobial Properties: Animal and test tube studies suggest that hesperidin has antimicrobial properties.
- Anti-glaucoma Properties: Animal and test tube studies suggest that hesperidin has anti-glaucoma properties.
There are some case studies regarding the benefits of Hesperidin 50%. For example, one study found that taking one tablet of diosmin/hesperidin (450/50 mg) by mouth twice daily for 90 days was effective for venous ulcers. Another study found that the mixture of hesperidin with other flavonoids (such as diosmin, troxerutin, rutin, and quercetin) reduced pain, swelling, bleeding, and painkiller use in two clinical trials on over 200 people.
The recommended dosage of Hesperidin 50% varies depending on the condition being treated. For example, one study used one tablet of diosmin/hesperidin (450/50 mg) taken by mouth twice daily for 90 days for venous ulcers. Another study used a dose of 500mg of hesperidin supplementation taken with food for cardioprotection in animal studies.
There are some potential side effects of Hesperidin 50%. For example, it might slow blood clotting and increase the risk of bleeding. In theory, it might make bleeding disorders worse. It might also lower blood pressure. In theory, taking Hesperidin might make blood pressure become too low in people who already have low blood pressure. Reported side effects include discomfort and rage in the stomach, diarrhea, and headache. However, in general, Hesperidin is well-tolerated and safe.
Sources:
- https://www.verywellhealth.com/what-you-need-to-know-about-hesperidin-89462
- https://www.emedicinehealth.com/what_is_hesperidin_good_for/article_em.htm
- https://www.webmd.com/vitamins/ai/ingredientmono-1030/diosmin
- https://www.webmd.com/vitamins/ai/ingredientmono-1033/hesperidin
- https://www.rxlist.com/hesperidin/supplements.htm
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952680/