7-oxo-DHEA

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7-oxo-DHEA, also known as 7-keto-DHEA, is a metabolite of dehydroepiandrosterone (DHEA) that is nonhormonal and does not convert back into DHEA. It is commonly used as a dietary supplement and has been shown to potentially increase metabolic rate and aid in fat loss. A typical supplemental dosage of 7-keto is 200-400mg daily in two divided doses (100-200mg), with some limited evidence suggesting that lower doses of 50-100mg may be effective. A systematic review of the impact of 7-keto-DHEA on body weight found that supplementation with 7-keto-DHEA resulted in a significant decrease in body weight, body mass index (BMI), and body fat percentage in humans. However, more research is needed to confirm these results.

The benefits of 7-oxo-DHEA supplementation include a potential increase in metabolic rate and aid in fat loss. A study published in the Journal of Nutritional Biochemistry found that 7-keto-DHEA supplementation increased metabolic rate in overweight adults. Another study published in the Journal of the International Society of Sports Nutrition found that 7-keto-DHEA supplementation in combination with exercise led to significant reductions in body weight and body fat percentage.

There are limited case studies regarding the benefits of 7-oxo-DHEA, but some studies have shown promise in its use for fat loss and weight management. A systematic review of the impact of 7-keto-DHEA on body weight found that supplementation with 7-keto-DHEA resulted in a significant decrease in body weight, body mass index (BMI), and body fat percentage in humans.

The recommended dosage of 7-oxo-DHEA is 200-400mg daily in two divided doses (100-200mg), with some limited evidence suggesting that lower doses of 50-100mg may be effective. It is important to follow the recommended dosage and speak with a healthcare provider before beginning supplementation.

Potential side effects of 7-oxo-DHEA include nausea, dizziness, and low blood pressure. It is possibly unsafe when used in high doses or long-term, and may increase the risk of serious side effects including cancer. Pregnant or breastfeeding women should avoid the use of 7-oxo-DHEA. It is important to speak with a healthcare provider before beginning supplementation to determine if it is safe for an individual to use.

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