Tripterygium 10:1
Tripterygium 10:1 is a concentrated extract of the Tripterygium wilfordii plant, which has been used in traditional Chinese medicine for centuries to treat various inflammatory and autoimmune diseases. Tripterygium 10:1 has significant anti-inflammatory and immunosuppressive properties and has been used to treat conditions such as rheumatoid arthritis and diabetic nephropathy.
A systematic review of randomized clinical trials of Tripterygium wilfordii for rheumatoid arthritis showed that it has beneficial effects in improving RA symptoms. Another study found that Tripterygium wilfordii Hook F extracts were effective in treating rheumatoid arthritis and had a better safety profile than methotrexate. A meta-analysis based on the duration of medication showed that Tripterygium-derived glycosides were effective in treating diabetic nephropathy after 3 and 6 months.
The recommended dosage of Tripterygium 10:1 varies depending on the condition being treated and the formulation of the product, but generally ranges from 60 to 180 mg per day. However, it is important to note that drugs containing Tripterygium wilfordii have a narrow therapeutic window and can cause adverse effects in clinical application. Therefore, it is recommended to consult a healthcare professional before using Tripterygium 10:1 and to closely monitor any potential side effects.
Sources:
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183448/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911475/
- https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/tripterygium-wilfordii
- https://arthritis-research.biomedcentral.com/articles/10.1186/s13075-018-1563-6
- https://www.frontiersin.org/articles/10.3389/fphar.2019.01250/full
- https://www.frontiersin.org/articles/10.3389/fendo.2021.656621/full
