GPLC (Glycine Propionyl-L-Carnitine)
Glycine Propionyl-L-Carnitine (GPLC) is an ester of Propionyl L-Carnitine that includes glycine. It is a nutritional supplement known for its vasodilatory effect, which increases blood flow, muscle pumps, and improves nitric oxide health.
GPLC offers various benefits, such as:
- Boosting nitric oxide levels, which helps stimulate muscle growth.
- Aiding in fat reduction.
- Reducing oxidative damage from free radicals.
- Improving physical performance and body composition.
- Enhancing blood circulation and promoting cardiovascular health.
- Increasing sexual potency.
Case Studies and URLs
A study conducted by Jacobs et al. (2010) examined the effects of chronic GPLC supplementation on 45 resistance-trained men. The participants were divided into three groups, consuming either 1.5g, 3g, or 4.5g of GPLC per day for 28 days. The study found that a daily dose of 1.5g of GPLC resulted in improvements in peak power and mean power compared to baseline values. The full study can be found here: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984406/].
Another study demonstrated that short-term administration of GPLC significantly elevated levels of nitric oxide metabolites at rest in both sedentary and trained individuals. The full study can be found here: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211291/].
The recommended dosage for GPLC varies depending on the specific form and purpose of use. For Glycine Propionyl L-Carnitine, a dosage range of 1,000-4,000 mg per day is suggested. However, the study by Jacobs et al. (2010) found that a daily dose of 1.5g of GPLC was the most beneficial amount for resistance-trained men.
Potential Side Effects
While side effects of GPLC are generally rare, some possible side effects include increased appetite, sleeplessness, and increased body odor. It is essential to consult with a healthcare professional before starting any supplementation, especially if you have any pre-existing medical conditions or are taking medications.
Sources
- https://www.moremuscle.com/amixpro-series/gplc-glycine-propionyl-l-carnitine-90-capsules-9371.html
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674410/
- https://www.healthline.com/nutrition/l-carnitine
- https://www.mrsupplement.com.au/gplc-review
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984406/
- https://www.mensjournal.com/food-drink/glycine-propionyl-l-carnitine
- https://examine.com/supplements/carnitine/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211291/
