Epimedium 50% Icariin
Epimedium 50% Icariin is a supplement derived from the Epimedium plant, also known as horny goat weed. It contains icariin, a prenylated glycoside flavonoid that is considered the active ingredient.
Here are some benefits of Epimedium 50% Icariin:
- Improved bone health: A human study on postmenopausal women and bone health noted that 60mg Icariin daily was active and might serve as the lowest active dose currently known.
- Antioxidant activity: Icariin has been shown to upregulate antioxidant activity and inhibit inflammation and oxidative stress in the brain.
- Testosterone boosting effects: Testosterone boosting effects in rats have been noted at a dosage of 200mg/kg of a 40% extract (80mg/kg Icariin).
- Improved immune response: In mice, icariin enhanced the Th1 immune response, which should help fight infections.
- Improved sexual function: Epimedium has been used traditionally to treat erectile dysfunction, and icariin has been shown to promote blood flow and treat various cardiovascular diseases.
There are several case studies regarding the benefits of Epimedium 50% Icariin. For example, a study found that icariin is effective in inhibiting human PDE5, the substance that blocks erections, in test tubes. Another study found that icariin improved symptoms in mice with multiple sclerosis by suppressing Th1. However, there have not been enough studies to recommend the use of this herb and to ensure its safety.
The recommended dosage for Epimedium 50% Icariin varies depending on the source. According to one source, commercially-available supplements contain 600 – 1,000 mg of the extract per tablet or capsule and recommend taking it once daily. Another source recommends a daily dose of 200mg of Horny Goat Weed 50%.
There are potential side effects associated with Epimedium 50% Icariin. For example, people who have a known sensitivity to Epimedium or are taking aromatase inhibitors such as anastrozole, exemestane, and letrozole should avoid it. Additionally, there have not been enough studies to ensure its safety.
Sources:
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400143/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575936/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898177/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804294/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445243/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330619/
