Curcumin 95%

Curcumin 95% is a natural compound found in turmeric, which is commonly used as a spice in Indian cuisine. It has anti-inflammatory and antioxidant properties, making it a popular supplement for various health conditions. However, ingesting curcumin by itself does not lead to the associated health benefits due to its poor bioavailability. Therefore, it is often combined with black pepper or with other substances to improve its absorption.

Studies have shown that curcumin can alleviate various conditions, from chronic pain to depression. It has been found to be effective in reducing inflammation and increasing the levels of endogenous antioxidants in the body. Curcumin has also been shown to improve symptoms of depression and anxiety and in pain and function in osteoarthritis. Reductions in LDL cholesterol, blood-glucose, and blood-pressure are possible, but the research on these outcomes is limited and less consistent.

Several clinical trials have supported the safety and efficacy of curcumin at doses as high as 12 g/day over 3 months. However, studies using high doses of curcumin have reported some mild adverse effects, including nausea, diarrhea, headache, skin rash, and yellow stool. Pregnant women should not use turmeric supplements.

One study found that supplementation with curcumin can be used instead of standard management such as nonsteroidal anti-inflammatory drugs (NSAIDS) for knee osteoarthritis. Another study showed that curcumin supplementation improved cognitive function in healthy elderly individuals. A dose escalation trial in 24 adults found that single oral dosages up to 12 g were safe, and adverse effects were mild.

The recommended dosage of Curcumin 95% varies depending on the condition being treated. However, most studies have used doses between 4000 and 8000 mg/day and of doses up to 12,000 mg/day of 95% concentration of three curcuminoids: curcumin, bisdemethoxycurcumin, and demethoxycurcumin. It is important to consult with a healthcare provider before taking any supplements.

Sources:

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664031/
2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535097/
3. https://examine.com/supplements/curcumin/
4. https://lpi.oregonstate.edu/mic/dietary-factors/phytochemicals/curcumin
5. https://www.mdpi.com/2304-8158/6/10/92
6. https://www.webmd.com/diet/supplement-guide-turmeric