Creatine AKG
Creatine AKG is a combination of creatine and alpha-ketoglutarate (AKG). Creatine is a molecule that is produced in the body from amino acids, primarily in the liver, kidneys, and pancreas. It stores high-energy phosphate groups in the form of phosphocreatine, which are donated to ADP to regenerate it to ATP, the primary energy source for muscle contraction. AKG is an intermediate in the Krebs cycle, which is involved in energy production. The combination of creatine and AKG is thought to enhance the absorption and utilization of creatine by muscle cells.
The benefits of Creatine AKG include improved exercise performance, increased strength and power output during resistance exercise, and modestly increased lean mass when used in conjunction with resistance exercise. A meta-analysis of 22 studies found that creatine supplementation increased lean tissue mass and muscle strength in older adults aged 57-70.
The recommended dosage of Creatine AKG is not established. However, a typical dose of creatine monohydrate is 5 grams per day, taken with food or a carbohydrate-containing beverage to enhance absorption.
Potential side effects of creatine supplementation include diarrhea and nausea when too much creatine is taken at one time. In this case, doses should be spread out throughout the day and taken with food or a carbohydrate-containing beverage to enhance absorption. There are few reports that creatine supplementation has protective effects in consumers.
There are no specific case studies regarding the benefits of Creatine AKG. However, several studies have shown that creatine supplementation increases blood, muscle, and brain creatine content, which can improve exercise performance. Studies also suggest that L-arginine may increase creatine synthesis in addition to increasing the rate of delivery of creatine to the muscle increasing.
Sources:
- https://examine.com/supplements/creatine/
- https://pubmed.ncbi.nlm.nih.gov/10999421/
- https://supplements.selfdecode.com/blog/creatine-nitrate/
- https://www.webmd.com/vitamins/ai/ingredientmono-144/alpha-ketoglutarate-akg
- https://www.mdpi.com/2072-6643/14/5/1035
- https://core.ac.uk/download/pdf/29843795.pdf
