Cocoa 10% Theobromine P.E.

Cocoa 10% Theobromine P.E. is an extract from the leaves and seeds of the cacao plant, with a 10% concentration level of the alkaloid theobromine. Theobromine is a bitter, crystalline substance that is similar to caffeine but has a longer half-life, meaning it remains in the body for longer periods. Cocoa 10% Theobromine P.E. is used as a vasodilator, a diuretic aid, and a heart stimulant

Research has suggested that theobromine may provide benefits such as:

• Increasing energy and alertness
• Reducing inflammation
• Improving cognitive functions
• Improving blood flow
• Lowering blood pressure
• Elevating HDL-cholesterol concentrations
• Modulating airways
• Increasing enamel hardness

A randomized controlled trial found that cocoa and theobromine consumption increased HDL-cholesterol concentrations. Another study found that consuming theobromine from chocolate may provide euphoric feelings and have mild anti-depressive effects. Additionally, a review of studies suggested that theobromine may exert some positive effects in different human pathologies.

Dosage and Side Effects

The recommended dosage for theobromine depends on several factors such as age, health, and other conditions. Theobromine appears to be safe when consumed between 300 – 600 milligrams per day. However, it is important to note that theobromine can cause side effects, such as nausea, vomiting, and tremors, especially when taken in high doses. Additionally, it may interact with certain medications, such as MAOIs, phenylpropanolamine, and theophylline

Case Studies

Several studies have been conducted on the effects of theobromine. A randomized controlled trial found that cocoa and theobromine consumption increased HDL-cholesterol concentrations. Another study found that consuming theobromine from chocolate may provide euphoric feelings and have mild anti-depressive effects. A review of studies suggested that theobromine may exert some positive effects in different human pathologies. Additionally, a study found that theobromine is responsible for the effects of cocoa on the antibody immune status of rats. However, it is important to note that most studies on theobromine have been conducted on animals and more research is needed to fully understand its benefits in humans.

Sources

1. https://www.science.gov/topicpages/t/theobromine
2. https://draxe.com/nutrition/theobromine-benefits/
3. https://www.ahajournals.org/doi/10.1161/circulationaha.108.827022
4. https://efsa.onlinelibrary.wiley.com/doi/pdf/10.2903/j.efsa.2008.725
5. https://www.researchgate.net/publication/236225148_Effect_of_cocoa_and_theobromine_consumption_on_serum_HDL-cholesterol_concentrations_A_randomized_controlled_trial
6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335269/
7. https://www.researchgate.net/publication/323830750_Theobromine_Is_Responsible_for_the_Effects_of_Cocoa_on_the_Antibody_Immune_Status_of_Rats
8. https://wap.21food.com/products/high-quality-cocoa-seed-extrac-1713901.html
9. https://damecacao.com/theobromine-vs-caffeine/
10. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672386/
11. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335269/