Sodium Caprate(Capsorb)
Sodium Caprate (Capsorb) is a compound produced through the neutralization of decanoic acid or saponification of its triglyceride esters with sodium. It is a medium-chain fatty acid and is well-known for its absorption-enhancing properties. Sodium Caprate increases the paracellular permeability through the intestinal epithelium, which improves the absorption of drugs and nutrients. It is approved as a food additive in the United States.
Benefits of Sodium Caprate:
- Improves the absorption of drugs and nutrients
- Enhances the transport of drugs across the intestinal mucosa in cell culture systems and small animal species
- Can improve the oral delivery of antisense oligonucleotides
- Enables the blood pressure-lowering effect of Ile
The recommended dosage of Sodium Caprate is not clearly established. The appropriate dosage may depend on factors such as age, health, and other conditions. There are no known side effects of Sodium Caprate. However, it is recommended to consult a healthcare professional before taking Sodium Caprate, especially if you are pregnant, breastfeeding, or have any underlying medical conditions.
Case studies:
- Enhancement of Sodium Caprate on Intestine Absorption and Antidiabetic Action of Berberine
- Effect of sodium caprate on the intestinal absorption of two modified antisense oligonucleotides in pigs
- Sodium caprate enables the blood pressure-lowering effect of Ile
Sources:
- https://pubmed.ncbi.nlm.nih.gov/20237966/
- https://www.researchgate.net/publication/42255997
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850468/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795615/
- https://pubmed.ncbi.nlm.nih.gov/12393140/
- https://www.sciencedirect.com/science/article/am/pii/S0939641117308986
