Propionyl-L-Carnitine HCL
Propionyl-L-Carnitine (PLC) is a chemical that is naturally produced in the body and is related to two other compounds called L-carnitine and acetyl-L-carnitine. It helps the body to produce energy and is important for heart function, muscle movement, and many other body processes. It is used for chest pain, heart disease, heart failure, athletic performance, chronic fatigue, and many other conditions. Although there is no good scientific evidence to support many of these uses, some studies have suggested that PLC may offer some benefits for certain conditions.
Benefits of Propionyl-L-Carnitine HCL:
- Chest pain (angina): Taking propionyl-L-carnitine by mouth seems to help people with chest pain due to poor blood flow to the heart.
- Erectile dysfunction (ED): A daily dose of 2 grams of propionyl-L-carnitine has been used in combination with 50 mg of sildenafil (Viagra).
- Chronic fatigue syndrome (CFS): A combination of propionyl-L-carnitine and acetyl-L-carnitine has been used to treat CFS.
- Anaerobic work capacity and sport performance: Long-term supplementation of glycine propionyl-l-carnitine may enhance anaerobic work capacity and sport performance.
Dosage:
- The standard dose of L-carnitine is 500 to 2,000 milligrams per day.
- Propionyl-L-carnitine has most often been used by adults in doses of 1.5-2 grams by mouth daily for up to 6 months.
Side effects:
- PLC is generally safe when taken in appropriate doses.
- The most common side effects are gastrointestinal disturbances, such as nausea, vomiting, abdominal cramps, and diarrhea.
- Rare side effects may include muscle weakness in uremic patients, seizures in people with seizure disorders, and a fishy odor of bodily secretions.
Case studies:
- Long-term glycine propionyl-l-carnitine supplemention and paradoxical effects on repeated anaerobic sprint performance
- The nutraceutical value of carnitine and its use in dietary supplements
