Horse Chestnut 20% Aescin(15:1)

Horse Chestnut 20% Aescin(15:1) is a plant extract that contains a group of molecules known as aescins, which are beneficial to circulatory health. It is most often used for varicose veins and veinous insufficiency. Horse chestnut extract contains a substance that thins the blood, making it harder for fluid to leak out of veins and capillaries, which can help prevent water retention (edema) . The active component in horse chestnut is escin.

Benefits of Horse Chestnut 20% Aescin(15:1):

• Reduces some symptoms of poor blood circulation, such as varicose veins, pain, tiredness, swelling in the legs, itching, and water retention.
• Increases sperm density in men with fertility problems.
• Helps treat chronic venous insufficiency.

Recommended dosage:

Horse chestnut extract has most often been used by adults in doses of 300-600 mg by mouth daily for 8-12 weeks. Horse chestnut tends to be taken in the 400-600mg range, although it seems that the overall dose is less important than the standardization for aescin which should ultimately reach 100-150mg daily. Supplementation tends to be divided into two daily doses divided by 12 hours.

Potential side effects:

Standardized horse chestnut seed extract products are likely safe for most people when used short-term. Only use products which have had esculin, a toxic substance, removed. Horse chestnut products can sometimes cause side effects such as dizziness, headache, stomach upset, and itching. Some people are allergic to horse chestnut. Nausea, digestive upsets, vertigo, and severe pain are some of the undesirable effects that may occur. If these symptoms occur after taking horse chestnut extract, it is advised to consult a doctor.

Case studies:

• Six placebo-controlled studies (543 participants) reported a clear reduction of leg pain when the herbal extract was compared with placebo.
• Bassler et al. conducted a study on the bioavailability of beta-aescin from horse chestnut seed extract and found that it was effective in treating edema.
• Rudofsky et al. conducted a double-blind study on the edema-protective effect and clinical efficacy of horse-chestnut seed extract and found that it was effective in treating edema.
• Schrader et al. conducted a study comparing the bioavailability of beta-aescin after single oral administration of two different drug formulations containing an extract of horse-chestnut seeds and found that both formulations were effective in treating edema.

Sources:

1. https://www.webmd.com/vitamins/ai/ingredientmono-1055/horse-chestnut
2. https://examine.com/supplements/horse-chestnut/
3. https://www.rxlist.com/horse_chestnut/supplements.htm
4. https://www.medicalnewstoday.com/articles/horse-chestnut
5. https://www.drugs.com/npp/horse-chestnut.html
6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144685/