Gotu Kola 4:1 P.E.
Gotu Kola 4:1 P.E. is a dietary supplement made from the extract of the Gotu Kola plant. It is a concentrated form of the herb that is four times stronger than regular Gotu Kola extract. Gotu Kola has been used for centuries in traditional medicine to treat various conditions such as anxiety, wound healing, and venous insufficiency.
The benefits of Gotu Kola 4:1 P.E. include improved cognitive function, reduced anxiety, and enhanced mood state. According to a study, 500mg of centella asiatica twice daily has shown anxiety-reducing effects in humans and 750mg of a 5% asiaticoside extract has enhanced mood state.
Another study showed that Gotu Kola can improve skin barrier function and reduce edema. A clinical trial of Indonesian batik workers found that Gotu Kola and ceramide improved skin barrier function. A randomized, dose-ranging trial found that Gotu Kola can reduce edema and increased capillary filtration in venous hypertension.
The recommended daily dose of titrated extracts of C. asiatica standardized for asiaticoside, asiatic acid, and madecassic acid is 60 to 120 mg. However, the usual dose for Gotu Kola is 0.5 to 1 g three times a day. There are potential side effects such as hepatotoxicity in children, so it is important to consult with a healthcare professional before taking this supplement.